哪有情可长
(2026-03-30 22:58):
#paper Sub-pangenome analysis reveals structural variants associated with fruit color and bacterial wilt resistance in eggplant， Nature Communication，23 February 2026，doi：10.1038/s41467-026-69764-8.
茄子是全球范围内重要的茄科蔬菜作物，其产量在茄科作物中位居第二，仅次于马铃薯和番茄。然而，关于其起源与驯化历史的科学问题至今仍存争议。为系统解析茄子种质资源的遗传多样性与群体结构，并为后续从头基因组测序与组装提供代表性材料，研究人员对全球 226 份茄子资源开展了重测序分析。该群体包括 219 份普通茄子、2 份近缘野生种、4 份红茄及 1 份野生茄子，主要分布于东亚和东南亚这一重要驯化中心区域，其中 198 份为本研究新测数据。群体结构分析加群体分化分析显示东南亚和欧美的群体的遗传多样性较高。而中国的表现出一定程度的遗传收敛。然后找了17份代表的材料构建了泛基因组，找到了一些结构变异影响群体特性、适应性及生物功能。
Nature Communications,
2026-2-23.
DOI: 10.1038/s41467-026-69764-8
Sub-pangenome analysis reveals structural variants associated with fruit color and bacterial wilt resistance in eggplant
Abstract:
Abstract<br> <br> Eggplant (<br> <i>Solanum melongena</i><br> L.) is a globally important Solanaceae crop, yet trait-relevant genomic variants remain poorly characterized. Here, we perform population genomic analyses of 226 eggplant accessions sampled mainly from a major domestication center spanning Southeast Asia and South China, and find that genetic relationships closely track geographic origin. We generate chromosome-scale assemblies for 11 representative accessions using long-read sequencing and integrate six published genomes to build a pangenome resource. Using this resource, association scans identify a 12.4 Mb inversion on chromosome 10 segregating at 50.44% frequency that is strongly associated with fruit color, likely through hitchhiking with<br> <i>SmMYB1</i><br> . We also detect variants associated with bacterial wilt resistance, including a premature stop codon in<br> <i>SmCYP82D47</i><br> and copy number variations in<br> <i>SmEPS1</i><br> and<br> <i>SmRoq1</i><br> homologs. Together, our results illuminate the evolution and phenotypic impact of large structural variants and provide genomic resources for eggplant genetics and breeding.<br>
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